Best MLB Strikeout Pitcher Matchups — Wednesday, July 22, 2026
Top strikeout spot: Reid Detmers
Reid Detmers (LAA) is the best strikeout matchup on the board at 100, projected for about 5.3 K against STL. He's missing bats at a 27% clip — strikeouts per batter faced — and STL has been around league average, going down 20% of the time. He's lined up for about 23 batters, so the volume's there for a big number.
The rest of the top of the board
- Gerrit Cole (NYY) (100) — about 5.8 K vs PIT: a 24% K/BF arm into a lineup that whiffs 25% of the time.
- Cade Cavalli (WSH) (97) — about 5.4 K vs COL: a 26% K/BF arm into a lineup that whiffs 21% of the time.
- Peter Lambert (HOU) (93) — about 5.4 K vs MIA: a 25% K/BF arm into a lineup that whiffs 21% of the time.
- Kyle Bradish (BAL) (91) — about 5.4 K vs BOS: a 23% K/BF arm into a lineup that whiffs 22% of the time.
- Aaron Nola (PHI) (90) — about 5.1 K vs LAD: a 24% K/BF arm into a lineup that whiffs 20% of the time.
Whiffiest lineups to attack today
- PIT is striking out 25% of the time in this spot — Gerrit Cole is the arm to exploit it (100).
- BAL is striking out 24% of the time in this spot — Jake Bennett is the arm to exploit it (87).
- LAA is striking out 24% of the time in this spot — Hunter Dobbins is the arm to exploit it (72).
- CIN is striking out 24% of the time in this spot — Emerson Hancock is the arm to exploit it (78).
How to read these strikeout matchups
Each starter's score (0–100) weighs his strikeout ability against every hitter in the lineup, hand by hand, then factors in how deep he tends to pitch and his command. Higher means more whiffs point his way. The exact weighting is our own — we project a strikeout count and grade every start against what actually happened.